11q22.2q22.3 microdeletion syndrome

ORPHA: 444002

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with 11q22.2q22.3 microdeletion syndrome, sourced from HPO and Orphanet clinical annotations.

AnxietyHypotoniaGlobal developmental delayThin upper lip vermilionEpicanthusNarrow foreheadMicrognathiaPosteriorly rotated earsLow-set earsStrabismusPtosisMyopiaThick eyebrowCompulsive behaviorsShort attention spanDelayed speech and language developmentAutism with high cognitive abilitiesReduced eye contactHyperpigmentation of the skinHemangiomaBrachydactylySeizureMild intellectual disabilityDysarthriaObesityShort footHypoplasia of the corpus callosumDelayed gross motor developmentDroolingPoor head controlHigh, narrow palateClinodactyly of the 5th fingerDepressed nasal bridgeAttention deficit hyperactivity disorderBilateral single transverse palmar creasesEpidermal thickeningFeeding difficultiesAbnormal social behaviorDelayed myelinationNeurodevelopmental delayOral motor hypotoniaPapuleSmall handAtypical behavior

Classification & Codes

Orphanet Code

ORPHA:444002
11q22.2q22.3 microdeletion syndrome
OrphanetORPHA:444002
Treatments0 drug(s)
Symptoms on record44 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO