16p13.11 microduplication syndrome

ORPHA: 261243

Overview

16p13.11 microduplication syndrome is a recently described syndrome associated with variable clinical features including behavioral abnormalities, developmental delay, congenital heart defects and skeletal anomalies.

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with 16p13.11 microduplication syndrome, sourced from HPO and Orphanet clinical annotations.

DolichocephalyAutismAggressive behaviorPectus excavatumHand polydactylyArachnodactylyIntellectual disabilityGlobal developmental delayCraniosynostosisVentricular septal defectAtrial septal defectTetralogy of FallotTransposition of the great arteriesCoarctation of aortaPes planusLanguage impairmentAttention deficit hyperactivity disorderSchizophreniaJoint hypermobility

Classification & Codes

Orphanet Code

ORPHA:261243
16p13.11 microduplication syndrome
OrphanetORPHA:261243
Treatments0 drug(s)
Symptoms on record19 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO