20p12.3 microdeletion syndrome

ORPHA: 261295

Overview

20p12.3 microdeletion syndrome is a recently described syndrome characterized by Wolff-Parkinson-White syndrome (see this term), variable developmental delay and facial dysmorphism.

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with 20p12.3 microdeletion syndrome, sourced from HPO and Orphanet clinical annotations.

Narrow mouthMacrocephalyMalar flatteningEpicanthusFull cheeksHypertelorismHypoplasia of the maxillaLong philtrumThickened helicesWide nasal bridgeDownslanted palpebral fissuresPectus carinatumSeizureHypotoniaGlobal developmental delayAtrial septal defectWolff-Parkinson-White syndromeVentriculomegalyShort statureDepressed nasal bridgeMicrotiaBroad hallux phalanxBroad thumb

Classification & Codes

Orphanet Code

ORPHA:261295
20p12.3 microdeletion syndrome
OrphanetORPHA:261295
Treatments0 drug(s)
Symptoms on record23 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO