3MC syndrome

ORPHA: 293843

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with 3MC syndrome, sourced from HPO and Orphanet clinical annotations.

Hearing impairmentPtosisEpicanthus inversusHighly arched eyebrowRadioulnar synostosisLimited pronation/supination of forearmOrofacial cleftHypertelorismDownslanted palpebral fissuresTelecanthusBlepharophimosisAbnormal anterior chamber morphologyIntellectual disabilityCraniosynostosisDiastasis rectiLarge fleshy earsSupernumerary nippleScoliosisDownturned corners of mouthSpina bifida occultaHyperlordosisBilateral cryptorchidismPostnatal growth retardationLow-set earsAbnormal pinna morphologyUmbilical herniaCaudal appendageHip dislocationAbnormal nasal morphologyProminent coccyx

Classification & Codes

Orphanet Code

ORPHA:293843
3MC syndrome
OrphanetORPHA:293843
Treatments0 drug(s)
Symptoms on record30 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO