3MC syndrome 3

ICD-10: Q89.8ORPHA: 2662

Overview

3MC congenital syndrome associated with the COLEC10 gene on chromosome 8q24

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with 3MC syndrome 3, sourced from HPO and Orphanet clinical annotations.

HypertelorismBroad foreheadSensorineural hearing impairmentProminent nasal bridgeDepressed nasal bridgeBroad distal phalanx of fingerShort distal phalanx of fingerBroad hallux phalanxShort halluxAplasia/Hypoplasia of the distal phalanges of the toesBroad thumbMacrocephalyEpicanthusHypoplasia of the maxillaPtosisHoarse voiceExaggerated cupid's bowClinodactyly of the 5th fingerAplastic/hypoplastic toenailTented upper lip vermilionAbnormal cardiovascular system morphologyAtypical behaviorShort statureCognitive impairment

Classification & Codes

ICD-10 Code

Q89.8

Orphanet Code

ORPHA:2662
3MC syndrome 3
ICD-10Q89.8
OrphanetORPHA:2662
Treatments0 drug(s)
Symptoms on record24 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO