9q21.13 microdeletion syndrome

ORPHA: 531151

Overview

novel genetic disorder in which the q21.13 region of chromosome 9 is deleted, this deletion causes a variety of symptoms, including intellectual disability, developmental and speech delay, epilepsy, low muscle tone and moderate facial dysmorphy

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with 9q21.13 microdeletion syndrome, sourced from HPO and Orphanet clinical annotations.

CryptorchidismHydronephrosisGait disturbanceAbnormal heart morphologyGastrointestinal dysmotilityPtosisLong palpebral fissureDelayed speech and language developmentHip dysplasiaTalipesScoliosisDownturned corners of mouthInverted nipplesVertebral segmentation defectAplasia/Hypoplasia of the corpus callosumPostnatal growth retardationWide nasal ridgeAbnormal tongue morphologyAutistic behaviorSeizureCraniosynostosisGray matter heterotopiaSyringomyeliaPolydactyly

Classification & Codes

Orphanet Code

ORPHA:531151
9q21.13 microdeletion syndrome
OrphanetORPHA:531151
Treatments0 drug(s)
Symptoms on record24 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO