AA amyloidosis

ICD-10: E85ORPHA: 85443

Overview

protein deposition disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with AA amyloidosis, sourced from HPO and Orphanet clinical annotations.

FatigueAbnormality of the kidneyProteinuriaNephrotic syndromeAbnormal heart morphologyHypertrophic cardiomyopathyWeight lossMalabsorptionAbnormal EKGAbnormal pulmonary interstitial morphologySensorimotor neuropathyIncreased circulating immunoglobulin concentrationHepatic amyloidosisAlbuminuriaDecreased QRS voltagePeriorbital purpuraElevated circulating NT-proBNP concentrationMonoclonal light chain cardiac amyloidosisRenal interstitial amyloid depositsErectile dysfunctionIncreased circulating troponin I concentrationIncreased circulating troponin T concentrationRenal insufficiencyXerostomiaBruising susceptibilityAbnormal cardiac ventricle morphologyAnemiaDyspneaHepatomegalyObstructive sleep apneaHypoalbuminemiaElevated circulating alkaline phosphatase concentrationAbdominal distentionAbnormal cardiac atrium morphologyPostural hypotension with compensatory tachycardiaReduced factor X activityAutonomic erectile dysfunctionPeripheral neuropathyAbnormal salivary gland morphologyArrhythmiaConstrictive median neuropathyAbnormal autonomic nervous system physiologyPeripheral edemaPulmonary interstitial high-resolution computed tomography abnormalityJaw claudicationNonproductive coughAbnormal P waveHowell-Jolly bodiesMacroglossiaHoarse voiceDysphagiaGastrointestinal hemorrhageGastroparesisAbnormality of the gastrointestinal tract

Classification & Codes

ICD-10 Code

E85

Orphanet Code

ORPHA:85443
AA amyloidosis
ICD-10E85
OrphanetORPHA:85443
Treatments0 drug(s)
Symptoms on record54 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO