ABeta amyloidosis, Arctic type

ORPHA: 3247231 Treatment Available

Overview

Hereditary cerebral hemorrhage with amyloidosis (HCHWA), Arctic type is a form of HCHWA (see this term) characterized by an age of onset of 54-61 years and progressive Alzheimer's disease-like dementia, without intracerebral hemorrhages

Available Treatments (1)

DrugFormStatusCountriesLead Time
Patisiran
Orphan Cold Chain
IV infusion, 2 mg/mLFDA Approved6

Clinical Presentation

Signs and symptoms associated with ABeta amyloidosis, Arctic type, sourced from HPO and Orphanet clinical annotations.

Atypical behaviorFebrile seizure (within the age range of 3 months to 6 years)

Classification & Codes

Orphanet Code

ORPHA:324723
ABeta amyloidosis, Arctic type
OrphanetORPHA:324723
Treatments1 drug(s)
Symptoms on record2 signs
Statuspublished

Treatment Summary

Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO