acquired generalized lipodystrophy

ORPHA: 79086

Overview

complete generalized lipodystrophy that is charcterized by generalized disappearance of fat occurring during childhood and adolescence where normal body fat is present at birth

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with acquired generalized lipodystrophy, sourced from HPO and Orphanet clinical annotations.

Generalized lipodystrophyHyperinsulinemiaInsulin resistanceInsulin-resistant diabetes mellitusHepatic steatosisCardiomyopathyAutoimmunityAbnormal circulating lipid concentrationCalf muscle pseudohypertrophyProgeroid facial appearanceAbnormal cardiovascular system physiologyProteinuriaPolycystic ovariesHypertensionAcanthosis nigricansCirrhosisAcute pancreatitisHypertriglyceridemiaGeneralized hirsutismHepatomegalyMyopathyAbnormality of complement systemAccelerated skeletal maturationGeneralized hyperpigmentationPanniculitisLymphomaAstrocytomaUnicameral bone cyst

Classification & Codes

Orphanet Code

ORPHA:79086
acquired generalized lipodystrophy
OrphanetORPHA:79086
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
acquired generalized lipodystrophy | OrphanDrug