acral dystrophic epidermolysis bullosa

ORPHA: 158673

Overview

Acral dystrophic epidermolysis bullosa is a very rare subtype of dystrophic epidermolysis bullosa (DEB, see this term) characterized by blistering confined primarily to the hands and feet

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with acral dystrophic epidermolysis bullosa, sourced from HPO and Orphanet clinical annotations.

Thin skinPalmoplantar hyperkeratosisCutaneous photosensitivityTelangiectasiaPoikilodermaFragile skinMiliaDystrophic toenailEsophageal strictureAbnormality of the lower limbDermal atrophyCrusting erythematous dermatitisAbnormal blistering of the skinDystrophic fingernailsErythemaErythematous plaqueAcral blisteringAbnormality of the kneeRecurrent loss of toenails and fingernailsAbnormality of the elbow

Classification & Codes

Orphanet Code

ORPHA:158673
acral dystrophic epidermolysis bullosa
OrphanetORPHA:158673
Treatments0 drug(s)
Symptoms on record20 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO