acro-renal-ocular syndrome

ORPHA: 959

Overview

related disorders including Okihiro syndrome and Holt-Oram syndrome (see these terms). Transmission is autosomal dominant.

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with acro-renal-ocular syndrome, sourced from HPO and Orphanet clinical annotations.

Horseshoe kidneyAbnormal thumb morphologyAbnormal morphology of the radiusRenal malrotationCrossed fused renal ectopiaAplasia/Hypoplasia of the radiusShort distal phalanx of the thumbShort thumbBladder diverticulumConductive hearing impairmentSensorineural hearing impairmentStrabismusVisual impairmentOptic disc colobomaPreaxial hand polydactylyTriphalangeal thumbSandal gapHypoplasia of the ulnaRadial ray deficiencyOptic disc hypoplasiaRenal hypoplasia/aplasiaBroad hallux phalanxShort halluxShort palpebral fissureVesicoureteral refluxEpicanthusHypertelorismMicrocorneaPtosisCataractChorioretinal colobomaMicrophthalmiaColobomaIris colobomaNystagmusTetralogy of FallotToe syndactylyTalipesAganglionic megacolonVertebral fusionVertebral segmentation defectShort humerusFinger syndactylyPostnatal growth retardation

Classification & Codes

Orphanet Code

ORPHA:959
acro-renal-ocular syndrome
OrphanetORPHA:959
Treatments0 drug(s)
Symptoms on record44 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO