acrofrontofacionasal dysostosis

MeSH: C538186ORPHA: 1784

Overview

dysostosis characterized

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with acrofrontofacionasal dysostosis, sourced from HPO and Orphanet clinical annotations.

HypospadiasBifid scrotumAbnormality of the genitourinary systemCleft palateHigh palateEverted lower lip vermilionBrachycephalyHypertelorismBroad foreheadBroad nasal tipDownslanted palpebral fissuresPtosisEyelid colobomaHypopigmented skin patchesBrushfield spotsBrachydactylyAnonychiaCerebral cortical atrophyMicromeliaDimple on nasal tipShort statureAbnormal epiphysis morphologyShort distal phalanx of fingerSevere intellectual disabilityBroad thumbMidface retrusionNon-midline cleft of the upper lipCamptodactyly of fingerAplasia/Hypoplasia of the eyebrow

Classification & Codes

MeSH Code

C538186

Orphanet Code

ORPHA:1784
acrofrontofacionasal dysostosis
MeSHC538186
OrphanetORPHA:1784
Treatments0 drug(s)
Symptoms on record29 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO