acromesomelic dysplasia, Hunter-Thompson type

ORPHA: 968

Overview

acromesomelic dysplasia that has material basis in mutation in AMDH gene which results in normal axial skeleton but fused bones in the located in hand or located in foot

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with acromesomelic dysplasia, Hunter-Thompson type, sourced from HPO and Orphanet clinical annotations.

BrachydactylyJoint stiffnessAbnormal speech patternAbnormal pelvic girdle bone morphologyScoliosisHip dislocationPatellar dislocationAbnormality of the ankleElbow dislocationAcromesomeliaCuboidal metacarpalAbnormally shaped carpal bonesBilateral single transverse palmar creasesTarsal synostosisSevere short-limb dwarfismShort thumbShort metacarpalCognitive impairment

Classification & Codes

Orphanet Code

ORPHA:968
acromesomelic dysplasia, Hunter-Thompson type
OrphanetORPHA:968
Treatments0 drug(s)
Symptoms on record18 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO