acute disseminated encephalomyelitis
MeSH: D004673ORPHA: 83597
Overview
encephalomyelitis characterized by inflammation located in brain and located in spinal cord that damages myelin
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with acute disseminated encephalomyelitis, sourced from HPO and Orphanet clinical annotations.
EncephalopathyDiffuse white matter abnormalitiesCNS demyelinationEEG with generalized slow activityAtypical behaviorIrritabilitySeizureAtaxiaMental deteriorationAbnormal cerebellum morphologyFeverNauseaAbnormal basal ganglia morphologyAbnormal spinal cord morphologyCerebral edemaHeadacheAbnormal periventricular white matter morphologyIncreased CSF protein concentrationAbnormal pyramidal signMyelitisAbnormal thalamic MRI signal intensityAbnormal brainstem MRI signal intensityInterictal EEG abnormalityDisseminated viral infectionAnti-myelin oligodendrocyte glycoprotein antibody positivityExcessive daytime somnolenceCSF lymphocytic pleiocytosisVisual lossAggressive behaviorComaHemiparesisConfusionMuscle weaknessVomitingAbnormal speech patternSomatic sensory dysfunctionRespiratory failure requiring assisted ventilationCranial nerve paralysisEEG with focal slow activityAtypical absence status epilepticusEEG with focal spikesEye movement-induced painNuchal rigidityOptic neuritisInvoluntary movementsViral hepatitisDiaphragmatic paralysisHypointensity of cerebral white matter on MRIHerpes simplex encephalitisPost-vaccination measlesPost-vaccination rubellaSevere Epstein Barr virus infectionSevere parainfluenza infection
Classification & Codes
MeSH Code
D004673Orphanet Code
ORPHA:83597acute disseminated encephalomyelitis
| MeSH | D004673 |
| Orphanet | ORPHA:83597 |
| Treatments | 0 drug(s) |
| Symptoms on record | 53 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO