acute promyelocytic leukemia

MeSH: D015473ORPHA: 520

Overview

acute myeloid leukemia characterized by accumulation of promyelocytes in the bone marrow and by a translocation between chromosomes 15 and 17

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with acute promyelocytic leukemia, sourced from HPO and Orphanet clinical annotations.

Gingival bleedingEpistaxisPetechiaeBruising susceptibilityPurpuraMuscle weaknessWeight lossThrombocytopeniaPancytopeniaDecreased total leukocyte countAbnormal bleedingAnemiaFeverAnorexiaVertigoExertional dyspneaDisseminated intravascular coagulationFatigueBone marrow hypercellularityChronic infectionEcchymosisGingival overgrowthDecreased total neutrophil countIncreased total leukocyte countAbdominal painBone painLymphadenopathyStomatitisHypofibrinogenemiaDiffuse alveolar hemorrhageOral cavity bleedingAddictive alcohol useProductive coughHematuriaMetrorrhagiaGangrene

Classification & Codes

MeSH Code

D015473

Orphanet Code

ORPHA:520
acute promyelocytic leukemia
MeSHD015473
OrphanetORPHA:520
Treatments0 drug(s)
Symptoms on record36 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO