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Adams-Oliver syndrome

MeSH: C538225ORPHA: 974

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

syndrome characterized by defects of the scalp (aplasia cutis congenita), abnormalities of the fingers, toes, arms and legs

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Adams-Oliver syndrome, sourced from HPO and Orphanet clinical annotations.

Cutis marmorataAplasia cutis congenitaCalvarial skull defectFailure to thriveAbnormality of the lower limbAbnormality of the upper limbAbsent handAplasia/Hypoplasia of the skinSparse hairAbsent toeHydrocephalusStrabismusCataractMicrophthalmiaBrachydactylySplit handTetralogy of FallotAbnormal pulmonary valve morphologyTalipesPulmonary artery atresiaAbnormal metacarpal morphologyFinger syndactylyShort distal phalanx of fingerIntellectual disabilitySeizureHemiparesisHypertoniaCirrhosisPortal hypertensionAscitesAlopeciaPremature birthHypoplastic fingernailAbsent fingernailThrombocytopeniaDecreased total leukocyte countEsophageal varixEncephalocelePulmonary arterial hypertensionPorencephalic cystGastrointestinal hemorrhageEEG abnormalityCongenital hepatic fibrosisPeriventricular leukomalaciaAplastic/hypoplastic toenailArteriovenous malformation

Classification & Codes

MeSH Code

C538225

Orphanet Code

ORPHA:974
Adams-Oliver syndrome
MeSHC538225
OrphanetORPHA:974
Treatments0 drug(s)
Symptoms on record46 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO