adenohypophysitis
ORPHA: 95512
Overview
autoimmune disease of the pituitary gland which can present with varying degrees of pituitary hormonal impairment and/or with symptoms related to pituitary enlargement. It predominantly affects young women in pregnancy or the peripartum period
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with adenohypophysitis, sourced from HPO and Orphanet clinical annotations.
PanhypopituitarismAmenorrheaBlurred visionImpotenceIncreased circulating prolactin concentrationPallorOrthostatic hypotensionNormochromic anemiaNauseaHeadacheHyposthenuriaProgressive visual field defectsDecreased circulating cortisol levelGonadotropin deficiencyDecreased serum estradiolSecondary growth hormone deficiencyPituitary hypothyroidismAdrenocorticotropin deficient adrenal insufficiencyAdrenocorticotropic hormone deficiencyAbnormal size of pituitary glandAbnormal thalamic MRI signal intensityDecreased female libidoDecreased serum testosterone concentrationDecreased male libidoSensorineural hearing impairmentDiplopiaHashimoto thyroiditisHyponatremiaAntinuclear antibody positivityPoor appetiteChronic lymphocytic meningitisReduced circulating prolactin concentration
Classification & Codes
Orphanet Code
ORPHA:95512adenohypophysitis
| Orphanet | ORPHA:95512 |
| Treatments | 0 drug(s) |
| Symptoms on record | 32 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO