adult polyglucosan body disease
MeSH: C564878ORPHA: 206583
Overview
Adult polyglucosan body disease (APBD) is a glycogen storage disease of adults characterized by progressive upper and lower motor neuron dysfunction, progressive neurogenic bladder and cognitive difficulties that can lead to dementia
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with adult polyglucosan body disease, sourced from HPO and Orphanet clinical annotations.
Neurogenic bladderUrinary incontinenceAtypical behaviorDementiaIntellectual disabilityAtaxiaSpasticityHemiparesisGait disturbanceMuscle weaknessLimitation of joint mobilityAbnormality of extrapyramidal motor functionUrinary bladder sphincter dysfunctionDistal sensory impairmentEMG abnormalityAbnormal pyramidal signPeripheral neuropathySkin ulcer
Classification & Codes
MeSH Code
C564878Orphanet Code
ORPHA:206583adult polyglucosan body disease
| MeSH | C564878 |
| Orphanet | ORPHA:206583 |
| Treatments | 0 drug(s) |
| Symptoms on record | 18 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO