African iron overload

MeSH: C537904ORPHA: 139507

Overview

hemochromatosis characterized by a predisposition to iron loading that is exacerbated by excessive intake of dietary iron, commonly related to consumption of tradition beer brewed in non-galvanized steel drums

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with African iron overload, sourced from HPO and Orphanet clinical annotations.

Increased circulating ferritin concentrationHepatic fibrosisHepatic periportal necrosisViral hepatitisHepatitisElevated transferrin saturationElevated hepatic iron concentrationAbnormality of the genital systemDiabetes mellitusHepatic steatosisHepatocellular carcinomaMicronodular cirrhosisAbnormal heart morphologyCongestive heart failureHepatomegalyIncreased circulating cortisol levelAbnormal adrenal morphologyAbnormal thyroid morphologyAbnormal pancreas morphologyHepatic bridging fibrosisChronic infectionDecreased circulating vitamin C concentrationOsteoporosisPeritonitisEsophageal carcinoma

Classification & Codes

MeSH Code

C537904

Orphanet Code

ORPHA:139507
African iron overload
MeSHC537904
OrphanetORPHA:139507
Treatments0 drug(s)
Symptoms on record25 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO