African trypanosomiasis
MeSH: D014353ORPHA: 3385
Overview
parasitic disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with African trypanosomiasis, sourced from HPO and Orphanet clinical annotations.
Abnormality of the nervous systemExcessive daytime somnolenceSleep disturbanceSleep-wake cycle disturbanceCataplexyPeriodic feverApathyPruritusMuscle weaknessHepatosplenomegalySplenomegalyWeight lossHepatomegalyHeadacheAbnormal rapid eye movement sleepAbnormal cerebral white matter morphologyLymphadenopathyAbnormal EKGAbnormal central motor functionFatigueAbnormal basal ganglia MRI signal intensityRigorsInsomniaBrain imaging abnormalityUrinary incontinenceRenal insufficiencyAbnormality of the menstrual cycleKeratitisConjunctivitisDiplopiaAtypical behaviorAggressive behaviorIrritabilityAnxietyGynecomastiaInfertilityImpotenceAbnormality of the endocrine systemAbnormality of renin-angiotensin systemJaundiceIritisChoreoathetosisHemiparesisGait disturbanceTremorPsychotic mentationAlopeciaThird degree atrioventricular blockVomitingDiarrheaNauseaVentriculomegalyAbnormal speech patternAkinesiaFasciculationsPrimitive reflexArthralgiaParesthesiaParalysisSomatic sensory dysfunctionInvoluntary movementsReduced consciousnessDisseminated intravascular coagulationCranial nerve paralysisMotor polyneuropathyImpaired proprioceptionSecond degree atrioventricular blockAbnormality of circulating cortisol levelAbnormal growth hormone levelAbnormal prolactin levelOptic neuritisDyskinesiaHallucinationsPapilledemaSeizureComaPremature birthCongestive heart failurePericarditisMyelopathyArrhythmiaMyelitisMyocarditisErythematous maculeDelirium
Classification & Codes
MeSH Code
D014353Orphanet Code
ORPHA:3385African trypanosomiasis
| MeSH | D014353 |
| Orphanet | ORPHA:3385 |
| Treatments | 0 drug(s) |
| Symptoms on record | 85 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO