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alpha chain disease

ICD-10: C88.3MeSH: D007161ORPHA: 100025

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

heavy chain disease that results from an overproduction of alpha antibodies (IgA)

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with alpha chain disease, sourced from HPO and Orphanet clinical annotations.

MalabsorptionAbnormal small intestine morphologyDysgammaglobulinemiaAnemiaAbdominal painImmunodeficiencyHypocalcemiaGrowth delayAscitesAlopeciaSplenomegalyFeverHepatomegalyLymphomaLymphadenopathy

Classification & Codes

ICD-10 Code

C88.3

MeSH Code

D007161

Orphanet Code

ORPHA:100025
alpha chain disease
ICD-10C88.3
MeSHD007161
OrphanetORPHA:100025
Treatments0 drug(s)
Symptoms on record15 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO