alternating hemiplegia of childhood
MeSH: C536589ORPHA: 2131
Overview
hemiplegia characterized by recurrent episodes of temporary weakness or complete paralysis on one or both sides of the body
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with alternating hemiplegia of childhood, sourced from HPO and Orphanet clinical annotations.
Gastrointestinal dysmotilityAbnormality of the gastrointestinal tractEpisodic hemiplegiaEsotropiaExotropiaNystagmusAtypical behaviorDelayed speech and language developmentPallorIntellectual disabilitySeizureAtaxiaDystoniaFailure to thriveVomitingDiarrheaDysphagiaConstipationAnorexiaTetraparesisAbdominal distentionMydriasisAbnormal autonomic nervous system physiologyAbnormal involuntary eye movementsNeurodevelopmental delayFlushingOral-pharyngeal dysphagiaFacial hypotoniaHigh foreheadOculomotor apraxiaEmotional labilityAggressive behaviorHyperhidrosisHypotoniaDysarthriaChoreoathetosisAreflexiaTremorHyperreflexiaDehydrationRigidityBilateral tonic-clonic seizureChoreaRespiratory distressApneaStatus epilepticusExaggerated cupid's bowHeadacheProgressive neurologic deteriorationBulbar signsDownturned corners of mouthAspirationAbnormal T-waveParoxysmal dyskinesiaAbnormal pyramidal signFocal motor seizureCardiac conduction abnormalityOcular flutterSkewfootThin eyebrowImpulsivityCardiomyopathyArrhythmia
Classification & Codes
MeSH Code
C536589Orphanet Code
ORPHA:2131alternating hemiplegia of childhood
| MeSH | C536589 |
| Orphanet | ORPHA:2131 |
| Treatments | 0 drug(s) |
| Symptoms on record | 63 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO