aminopterin/methotrexate embryofetopathy
ORPHA: 1908
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with aminopterin/methotrexate embryofetopathy, sourced from HPO and Orphanet clinical annotations.
HydrocephalusEpicanthusMandibular prognathiaHypertelorismWide nasal bridgeProptosisAnencephalySkeletal dysplasiaMicromeliaMesomeliaShort statureUnderdeveloped supraorbital ridgesCleft palateMicrocephalyMicrognathiaIntrauterine growth retardationTalipesEncephaloceleMeningoceleNon-midline cleft of the upper lipAbnormal fingernail morphologyHoloprosencephalyVentricular septal defectTetralogy of FallotSitus inversus totalisSmall nailPulmonary artery atresiaFinger syndactylyAplasia/Hypoplasia of the cerebellumAplasia/Hypoplasia of the corpus callosumAplasia/Hypoplasia of the thumbSpinal dysraphismPosteriorly rotated ears
Classification & Codes
Orphanet Code
ORPHA:1908aminopterin/methotrexate embryofetopathy
| Orphanet | ORPHA:1908 |
| Treatments | 0 drug(s) |
| Symptoms on record | 33 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO