Antley-Bixler syndrome

ICD-10: Q87.0MeSH: D054882ORPHA: 2432

Overview

autosomal recessive disease that is characterized at birth or prenatally by malformations and deformities affecting the majority of the skeleton and other areas of the body with autosomal recessive inheritance of the FGFR2 gene

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Antley-Bixler syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormal cranial suture/fontanelle morphologyBroad foreheadMicrocorneaMicrophthalmiaLarge for gestational ageRecurrent respiratory infectionsHepatomegalyRespiratory insufficiencyAbnormal calvaria morphologyCorneal opacityMedian cleft palatePtosisCraniosynostosisHypotelorismGlossoptosis

Classification & Codes

ICD-10 Code

Q87.0

MeSH Code

D054882

Orphanet Code

ORPHA:2432
Antley-Bixler syndrome
ICD-10Q87.0
MeSHD054882
OrphanetORPHA:2432
Treatments0 drug(s)
Symptoms on record15 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO