arterial calcification of infancy

MeSH: C537440ORPHA: 51608

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

vascular disease that is characterized by generalized calcification of the arterial internal elastic lamina, leading to rupture of the lamina and occlusive changes in the tunica intima with stenosis and decreased elasticity of the vessel wall

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with arterial calcification of infancy, sourced from HPO and Orphanet clinical annotations.

HyperphosphaturiaCalcification of the auricular cartilageMyocardial calcificationSevere global developmental delayChoroidal neovascularizationEncephalomalaciaGangreneArterial calcificationGeneralized arterial calcificationCalcification of the aortaHepatic calcificationNephrocalcinosisHearing impairmentHypertensionCyanosisPolyhydramniosCoronary artery calcificationRespiratory distressOsteomalaciaHypophosphatemic ricketsMedial calcification of large arteriesEctopic calcificationFeeding difficultiesMedullary nephrocalcinosisMedial calcification of medium-sized arteriesFetal distressLeft ventricular systolic dysfunctionPeriarticular calcificationStapes ankylosisConductive hearing impairmentSensorineural hearing impairmentMixed hearing impairmentAbnormal retinal arterial/arteriolar morphologyIrritabilityEdemaFailure to thrive in infancyAscitesCardiomegalyPericardial effusionVentricular hypertrophyHydrops fetalisFeverVomitingArthralgiaFused cervical vertebraeStippled calcification of the shoulderStippled calcification of the elbowAbnormal calcification of the carpal bonesElevated alkaline phosphatase of bone originCortical nephrocalcinosisWeak pulseRetinal hemorrhageAngioid streaksSeizureStrokePulmonary arterial hypertensionTransient ischemic attackCerebral calcificationAortic dissection

Classification & Codes

MeSH Code

C537440

Orphanet Code

ORPHA:51608

arterial calcification of infancy

MeSH	`C537440`
Orphanet	`ORPHA:51608`
Treatments	0 drug(s)
Symptoms on record	59 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO