ataxia-deafness-intellectual disability syndrome

MeSH: C535295ORPHA: 1188

Overview

This syndrome is characterised by progressive ataxia beginning during childhood, deafness and intellectual deficit

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with ataxia-deafness-intellectual disability syndrome, sourced from HPO and Orphanet clinical annotations.

Joint hypermobilitySensorineural hearing impairmentStrabismusNystagmusIntellectual disabilityAtaxiaAbnormal palate morphologyDecreased nerve conduction velocityHypotoniaReduced tendon reflexesVentriculomegalyCerebral cortical atrophyAbnormal speech patternScoliosisSkeletal muscle atrophyEMG abnormalityAplasia/Hypoplasia of the cerebellum

Classification & Codes

MeSH Code

C535295

Orphanet Code

ORPHA:1188
ataxia-deafness-intellectual disability syndrome
MeSHC535295
OrphanetORPHA:1188
Treatments0 drug(s)
Symptoms on record17 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
ataxia-deafness-intellectual disability syndrome | OrphanDrug