atypical hemolytic uremic syndrome

ICD-10: D59.3MeSH: D065766ORPHA: 2134

Overview

complement deficiency that is characterized by mechanical hemolytic anemia, thrombocytopenia, and renal dysfunction

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with atypical hemolytic uremic syndrome, sourced from HPO and Orphanet clinical annotations.

ProteinuriaHematuriaAbnormality of blood and blood-forming tissuesThrombocytopeniaAcute kidney injuryMicroangiopathic hemolytic anemiaAbnormality of metabolism/homeostasisAbnormal circulating lactate dehydrogenase concentrationReduced circulating complement concentrationAbnormality of complement systemDecreased circulating complement factor I concentrationDecreased circulating complement factor B concentrationDecreased level of thrombomodulin

Classification & Codes

ICD-10 Code

D59.3

MeSH Code

D065766

Orphanet Code

ORPHA:2134
atypical hemolytic uremic syndrome
ICD-10D59.3
MeSHD065766
OrphanetORPHA:2134
Treatments0 drug(s)
Symptoms on record13 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO