atypical hemolytic uremic syndrome
ICD-10: D59.3MeSH: D065766ORPHA: 21341 Treatment Available
Overview
complement deficiency that is characterized by mechanical hemolytic anemia, thrombocytopenia, and renal dysfunction
Available Treatments (1)
| Drug | Form | Status | Countries | Lead Time |
|---|---|---|---|---|
| ravulizumab Orphan Cold Chain | Concentrate for solution for infusion | FDA Approved | 5 | — |
Clinical Presentation
Signs and symptoms associated with atypical hemolytic uremic syndrome, sourced from HPO and Orphanet clinical annotations.
ProteinuriaHematuriaAbnormality of blood and blood-forming tissuesThrombocytopeniaAcute kidney injuryMicroangiopathic hemolytic anemiaAbnormality of metabolism/homeostasisAbnormal circulating lactate dehydrogenase concentrationReduced circulating complement concentrationAbnormality of complement systemDecreased circulating complement factor I concentrationDecreased circulating complement factor B concentrationDecreased level of thrombomodulin
Classification & Codes
ICD-10 Code
D59.3MeSH Code
D065766Orphanet Code
ORPHA:2134atypical hemolytic uremic syndrome
| ICD-10 | D59.3 |
| MeSH | D065766 |
| Orphanet | ORPHA:2134 |
| Treatments | 1 drug(s) |
| Symptoms on record | 13 signs |
| Status | published |
Treatment Summary
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO