autosomal dominant complex spastic paraplegia type 9B

ORPHA: 447757

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with autosomal dominant complex spastic paraplegia type 9B, sourced from HPO and Orphanet clinical annotations.

Pes cavusSpastic gaitPostural tremorProgressive neurologic deteriorationSpastic dysarthriaUpper motor neuron dysfunctionLoss of ambulationBabinski signHyperactive patellar reflexMotor polyneuropathyProgressive gait ataxiaUpper limb hyperreflexiaDevelopmental cataractDementiaHypotoniaGastroesophageal refluxElbow flexion contractureAbsent Achilles reflexPeripheral axonal neuropathyFocal dystoniaAtrophy of the spinal cord

Classification & Codes

Orphanet Code

ORPHA:447757
autosomal dominant complex spastic paraplegia type 9B
OrphanetORPHA:447757
Treatments0 drug(s)
Symptoms on record21 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO