autosomal dominant nocturnal frontal lobe epilepsy
ORPHA: 98784
Overview
frontal lobe epilepsy that is characterized by autosomal dominant inheritance with childhood onset of clusters of brief nocturnal motor seizures with hyperkinetic or tonic manifestations
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with autosomal dominant nocturnal frontal lobe epilepsy, sourced from HPO and Orphanet clinical annotations.
Nocturnal seizuresMotor stereotypyParoxysmal dystoniaInvoluntary movementsUrinary incontinenceDepressionAnxietyHyperventilationFocal hyperkinetic seizureInterictal epileptiform activityEEG with focal spikesSleep walkingIncreased theta frequency activity in EEGSuicidal ideationCognitive impairmentAtypical behaviorMild intellectual disabilityPsychotic mentationBilateral tonic-clonic seizureAttention deficit hyperactivity disorderNREM parasomnia
Classification & Codes
Orphanet Code
ORPHA:98784autosomal dominant nocturnal frontal lobe epilepsy
| Orphanet | ORPHA:98784 |
| Treatments | 0 drug(s) |
| Symptoms on record | 21 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO