Axenfeld-Rieger syndrome

MeSH: C535679ORPHA: 782

Overview

autosomal dominant disease characterized by abnormalities of the front part of the eye, the anterior segment

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Axenfeld-Rieger syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormal anterior chamber morphologyPosterior embryotoxonAplasia/Hypoplasia of the irisEverted lower lip vermilionHearing impairmentGlaucomaMidface retrusionAbnormal cardiovascular system morphologyHypospadiasHypertelorismHypoplasia of the maxillaWide nasal bridgeTelecanthusHypodontiaMicrodontiaAbnormality of the hypothalamus-pituitary axisGrowth delayRedundant skinAnal stenosisDepressed nasal bridgeProminent forehead

Classification & Codes

MeSH Code

C535679

Orphanet Code

ORPHA:782
Axenfeld-Rieger syndrome
MeSHC535679
OrphanetORPHA:782
Treatments0 drug(s)
Symptoms on record21 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
Axenfeld-Rieger syndrome | OrphanDrug