axonal polyneuropathy associated with IgG/IgM/IgA monoclonal gammopathy

ORPHA: 209004

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with axonal polyneuropathy associated with IgG/IgM/IgA monoclonal gammopathy, sourced from HPO and Orphanet clinical annotations.

Impaired vibration sensation in the lower limbsProgressive peripheral neuropathyDemyelinating sensory neuropathyDistal sensory impairmentDistal amyotrophyMonoclonal immunoglobulin M proteinemiaMotor axonal neuropathyDemyelinating motor neuropathyChronic axonal neuropathyLower limb muscle weaknessEMG: slow motor conductionSensory axonal neuropathyProgressive gait ataxiaLower limb painAcroparesthesiaLymphomaMultiple myelomaIncreased circulating beta-2-microglobulin levelCryoglobulinemia

Classification & Codes

Orphanet Code

ORPHA:209004
axonal polyneuropathy associated with IgG/IgM/IgA monoclonal gammopathy
OrphanetORPHA:209004
Treatments0 drug(s)
Symptoms on record19 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO