basal laminar drusen
MeSH: C563034ORPHA: 75376
Overview
retinal drusen characterized by yellow-white deposits (drusen) that accumulate beneath the retinal pigment epithelium on Bruch membrane and that has material basis in mutations in the CFH gene on chromosome 1q31.3
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with basal laminar drusen, sourced from HPO and Orphanet clinical annotations.
Macular drusenYellow/white macular lesionVisual lossMacular dystrophyReticular pigmentary degenerationAbnormal retinal pigmentationMacular hyperpigmentationMetamorphopsiaPerifoveal ring of hyperautofluorescenceHyperautofluorescent macular lesionHypoautofluorescent macular lesionPhotophobiaMacular atrophyGranular macular appearancePeripapillary chorioretinal atrophyChoroidal neovascularizationSerous retinal detachmentMacular hemorrhageParacentral scotomaSubretinal fluid
Classification & Codes
MeSH Code
C563034Orphanet Code
ORPHA:75376basal laminar drusen
| MeSH | C563034 |
| Orphanet | ORPHA:75376 |
| Treatments | 0 drug(s) |
| Symptoms on record | 20 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO