behavioral variant of frontotemporal dementia

ORPHA: 275864

Overview

Behavioral variant of frontotemporal dementia (bv-FTD) is a form of frontotemporal dementia (FTD; see this term), characterized by progressive behavioral impairment and a decline in executive function with frontal lobe-predominant atrophy

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with behavioral variant of frontotemporal dementia, sourced from HPO and Orphanet clinical annotations.

Thickened nuchal skin foldAtypical behaviorHyperoralityRestlessnessAggressive behaviorInappropriate behaviorRestrictive behaviorMotor stereotypyDisinhibitionIrritabilityPersonality changesLack of insightMental deteriorationFrontotemporal dementiaMemory impairmentLoss of speechAphasiaDyscalculiaPoor speechFrontotemporal cerebral atrophyDyslexiaDysgraphiaEcholaliaEmotional dearthPerseverative thoughtAbnormal cerebral white matter morphologyEEG with continuous slow activityAbnormal brain FDG positron emission tomographyCollectionismPsychosisApathyGait disturbanceHyperreflexiaBilateral tonic-clonic seizureAbnormality of extrapyramidal motor functionMutismFasciculationsAstrocytosisUpper motor neuron dysfunctionAbulia

Classification & Codes

Orphanet Code

ORPHA:275864
behavioral variant of frontotemporal dementia
OrphanetORPHA:275864
Treatments0 drug(s)
Symptoms on record40 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO