beta-thalassemia intermedia

ORPHA: 231222

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

Beta-thalassemia (BT) intermedia is a form of BT (see this term) characterized by mild to moderate anemia which does not or only occasionally requires transfusion

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with beta-thalassemia intermedia, sourced from HPO and Orphanet clinical annotations.

OsteoporosisAnemia of inadequate productionPersistence of hemoglobin FDecreased mean corpuscular volumeAbnormality of the skeletal systemJaundicePallorExtramedullary hematopoiesisIncreased susceptibility to fracturesReduced bone mineral densityAbnormality of iron homeostasisErythroid hyperplasiaIncreased HbA2 hemoglobinHypercoagulabilitySkin ulcerProximal tubulopathyOsteopeniaCholelithiasisAbnormality of the liverDecreased liver functionHepatosplenomegalyAbnormality of the cardiovascular systemHigh-output congestive heart failureSplenomegalyIncreased total leukocyte countPulmonary arterial hypertensionHepatomegalyElevated hepatic iron concentrationHypogonadismDiabetes mellitusHypothyroidismHypoparathyroidismAdrenal insufficiencyCirrhosisHepatocellular carcinomaSpinal cord compression

Classification & Codes

Orphanet Code

ORPHA:231222

beta-thalassemia intermedia

Orphanet	`ORPHA:231222`
Treatments	0 drug(s)
Symptoms on record	36 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO