bilateral polymicrogyria
ORPHA: 268940
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with bilateral polymicrogyria, sourced from HPO and Orphanet clinical annotations.
Wide mouthTongue muscle weaknessMacrocephalyMicrognathiaLow-set earsSensorineural hearing impairmentDysarthriaFacial diplegiaTalipes equinovarusBilateral tonic-clonic seizureGeneralized myoclonic seizureGeneralized-onset seizureDroolingArthrogryposis multiplex congenita4-layered lissencephalyPseudobulbar paralysisCentral hypothyroidismFeeding difficultiesInfantile spasmsPerisylvian polymicrogyriaAbnormality of masticatory muscleAbnormal glossopharyngeal nerve morphologySeizureEsotropiaDelayed speech and language developmentMild intellectual disabilityGlobal developmental delayMental deteriorationMotor delayCerebellar atrophySpastic tetraparesisVentriculomegalyPseudobulbar signsModerate intellectual disabilityLanguage impairmentFunctional motor deficitAbnormal pyramidal signFocal-onset seizureAplasia/Hypoplasia of the brainstemCerebellar ataxia associated with quadrupedal gaitDyslexiaSpastic hemiparesisAplasia/Hypoplasia of the cerebral white matterCognitive impairment
Classification & Codes
Orphanet Code
ORPHA:268940bilateral polymicrogyria
| Orphanet | ORPHA:268940 |
| Treatments | 0 drug(s) |
| Symptoms on record | 44 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO