branchiootic syndrome

MeSH: C565171ORPHA: 52429

Overview

syndrome characterized by malformations of the outer, middle and inner ear and branchial and renal malformations. Mutations of the EYA1, SIX1 and SIX5 genes are associated with the syndrome

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with branchiootic syndrome, sourced from HPO and Orphanet clinical annotations.

Facial asymmetryMicrognathiaAbnormality of the outer earAbnormality of the inner earPreauricular skin tagConductive hearing impairmentSensorineural hearing impairmentAtresia of the external auditory canalPreauricular pitAbnormal middle ear morphologyBranchial fistulaFacial palsyCleft palateHearing impairmentAbnormal nasolacrimal system morphologyLip pit

Classification & Codes

MeSH Code

C565171

Orphanet Code

ORPHA:52429
branchiootic syndrome
MeSHC565171
OrphanetORPHA:52429
Treatments0 drug(s)
Symptoms on record16 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO