campomelic dysplasia

MeSH: D055036ORPHA: 140

Overview

osteochondrodysplasia that has material basis in a mutation in chromosome 17 which results in bowing in the located in tibia or located in femur

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with campomelic dysplasia, sourced from HPO and Orphanet clinical annotations.

Cleft palateMacrocephalyMicrognathiaShort neckNarrow chest11 pairs of ribsLaryngomalaciaRespiratory insufficiencyScoliosisRecurrent fracturesTracheomalaciaTracheobronchomalaciaHip dislocationTibial bowingShort long boneFibular hypoplasiaBowing of the long bonesSmall abnormally formed scapulaePoorly ossified cervical vertebraeHypoplastic inferior iliaFlat faceMale pseudohermaphroditismAmbiguous genitaliaHypertelorismLow-set earsProptosisTalipes equinovarusFemoral bowingShort statureSkin dimpleHydronephrosisHearing impairmentVentriculomegalyKyphosisAbnormality of the sense of smellDepressed nasal bridgeHypoplasia of olfactory tractAbnormal cardiovascular system morphology

Classification & Codes

MeSH Code

D055036

Orphanet Code

ORPHA:140
campomelic dysplasia
MeSHD055036
OrphanetORPHA:140
Treatments0 drug(s)
Symptoms on record38 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
campomelic dysplasia | OrphanDrug