Carney complex
MeSH: D056733ORPHA: 1359
Overview
autosomal dominant disease characterized by myxomas, spotty pigmentation of the skin and endocrine overactivity
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Carney complex, sourced from HPO and Orphanet clinical annotations.
Pigmented micronodular adrenocortical diseaseOvarian cystElevated circulating growth hormone concentrationEuthyroid multinodular goiterIncreased circulating prolactin concentrationMultiple lentiginesAtypical nevi in non-sun exposed areasIncreased circulating cortisol levelSpotty hyperpigmentationMultiple cafe-au-lait spotsGonadal neoplasmTesticular neoplasmCardiac myxomaPituitary growth hormone cell adenomaIncreased circulating insulin-like growth factor 1 concentrationCutaneous myxomaSertoli cell neoplasmBlue nevusAbnormal morphology of female internal genitaliaMacroorchidismTongue nodulesAtypical behaviorGynecomastiaOligozoospermiaHypertensionBruising susceptibilityHirsutismStriae distensaeStrokeMuscle weaknessGrowth abnormalityCongestive heart failureThromboembolismIncreased body weightNeoplasm of the stomachFibroadenoma of the breastNodular changes affecting the eyelidsDecreased fertility in malesAbnormal sperm motilityAbdominal obesityOvarian serous cystadenomaOvarian dermoid cystOvarian carcinomaDorsocervical fat padTesticular adrenal rest tumorEnchondromaParanasal sinus neoplasmDuctal carcinoma in situSchwannomaNeoplasm of the breastLeydig cell neoplasiaNeoplasm of the pharynxAbnormal hard palate morphologyEsophageal neoplasmMoon faciesTall staturePrecocious pubertyHepatocellular carcinomaThyroid carcinomaNeoplasm of the pancreasPapillary thyroid carcinomaDilatation of the cerebral arteryFollicular thyroid carcinomaNeoplasm of the rectum
Classification & Codes
MeSH Code
D056733Orphanet Code
ORPHA:1359Carney complex
| MeSH | D056733 |
| Orphanet | ORPHA:1359 |
| Treatments | 0 drug(s) |
| Symptoms on record | 64 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO