CHARGE syndrome

ICD-10: Q89.8MeSH: D058747ORPHA: 2662

Overview

syndrome that is characterized by a pattern of congenital anomalies including choanal atresia and malformations of the heart, inner ear, and retina

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with CHARGE syndrome, sourced from HPO and Orphanet clinical annotations.

HypertelorismBroad foreheadSensorineural hearing impairmentProminent nasal bridgeDepressed nasal bridgeBroad distal phalanx of fingerShort distal phalanx of fingerBroad hallux phalanxShort halluxAplasia/Hypoplasia of the distal phalanges of the toesBroad thumbMacrocephalyEpicanthusHypoplasia of the maxillaPtosisHoarse voiceExaggerated cupid's bowClinodactyly of the 5th fingerAplastic/hypoplastic toenailTented upper lip vermilionAbnormal cardiovascular system morphologyAtypical behaviorShort statureCognitive impairment

Classification & Codes

ICD-10 Code

Q89.8

MeSH Code

D058747

Orphanet Code

ORPHA:2662
CHARGE syndrome
ICD-10Q89.8
MeSHD058747
OrphanetORPHA:2662
Treatments0 drug(s)
Symptoms on record24 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO