Charlie M syndrome

ORPHA: 1406

Overview

syndrome characterised tongue anomalies and distal limb deficiencies.

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Charlie M syndrome, sourced from HPO and Orphanet clinical annotations.

Narrow mouthThin vermilion borderHypertelorismMicrognathiaBrachydactylySplit handAbnormal fingernail morphologyFinger syndactylyAbnormal toenail morphologyTooth agenesisNon-midline cleft of the upper lipShort philtrumWide nasal bridgeAbnormal metacarpal morphologyMacrotiaTriphalangeal thumb

Classification & Codes

Orphanet Code

ORPHA:1406
Charlie M syndrome
OrphanetORPHA:1406
Treatments0 drug(s)
Symptoms on record16 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
Charlie M syndrome | OrphanDrug