chromosome 16p11.2 deletion syndrome, 220kb

ORPHA: 261222

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with chromosome 16p11.2 deletion syndrome, 220kb, sourced from HPO and Orphanet clinical annotations.

Narrow mouthLow anterior hairlineOval faceProminent nasal bridgeRod-cone dystrophyRetinal dystrophyDelayed speech and language developmentArachnodactylyGlobal developmental delayNeonatal hypotoniaAttention deficit hyperactivity disorderVesicoureteral refluxAbnormality of the kidneyProteinuriaRenal agenesisAutistic behaviorIntellectual disabilitySeizureObesityHyperuricemiaAganglionic megacolonModerate receptive language delayChronic constipationChronic kidney diseaseMigraineKyphosis

Classification & Codes

Orphanet Code

ORPHA:261222
chromosome 16p11.2 deletion syndrome, 220kb
OrphanetORPHA:261222
Treatments0 drug(s)
Symptoms on record26 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO