chromosome 19p13.13 deletion syndrome

ORPHA: 357001

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with chromosome 19p13.13 deletion syndrome, sourced from HPO and Orphanet clinical annotations.

MacrocephalyAbnormal facial shapeProminent foreheadLong faceAnteverted naresStrabismusDownslanted palpebral fissuresPectus excavatumIntellectual disabilityGlobal developmental delayAttention deficit hyperactivity disorderFunctional abnormality of the gastrointestinal tractMacroglossiaNarrow mouthHigh palateThin upper lip vermilionBrachycephalyDolichocephalyMalar flatteningEpicanthusHypertelorismSmooth philtrumLow-set earsMacrotiaDeeply set eyeLong eyelashesOptic nerve hypoplasiaNystagmusOptic atrophyCafe-au-lait spotSeizurePes planusSandal gapDeep plantar creasesVomitingDiarrheaAbdominal painShort noseSyringomyeliaDepressed nasal bridgeChiari type I malformationHypoplasia of the frontal lobesCorpus callosum atrophyIncreased nuchal translucencyFeeding difficultiesClinodactylyLong fingers

Classification & Codes

Orphanet Code

ORPHA:357001
chromosome 19p13.13 deletion syndrome
OrphanetORPHA:357001
Treatments0 drug(s)
Symptoms on record47 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO