chromosome 1q41-q42 deletion syndrome

ORPHA: 250999

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with chromosome 1q41-q42 deletion syndrome, sourced from HPO and Orphanet clinical annotations.

CryptorchidismAbnormality of the genital systemCleft palateSubmucous cleft hard palateAbnormality of the faceCoarse facial featuresUnderdeveloped nasal alaeBroad nasal tipStrabismusDeeply set eyeAbnormality iris morphologyUpslanted palpebral fissureHypotelorismAtypical behaviorCongenital diaphragmatic herniaHypergonadotropic hypogonadismIntellectual disabilitySeizureGlobal developmental delayNeonatal hypotoniaHoloprosencephalyGrowth delayShort statureTalipes equinovarusSmall nailMorphological central nervous system abnormalityFrontal bossingPulmonary hypoplasiaDepressed nasal bridgeSevere global developmental delayHyposegmentation of neutrophil nucleiThick vermilion border

Classification & Codes

Orphanet Code

ORPHA:250999
chromosome 1q41-q42 deletion syndrome
OrphanetORPHA:250999
Treatments0 drug(s)
Symptoms on record32 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO