chromosome 22q11.2 microduplication syndrome

MeSH: C567224ORPHA: 1727

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with chromosome 22q11.2 microduplication syndrome, sourced from HPO and Orphanet clinical annotations.

HydronephrosisCleft palateMicrocephalyNarrow faceEpicanthusHypertelorismSmooth philtrumMicrognathiaHigh foreheadHearing impairmentWide noseDepressed nasal ridgeDownslanted palpebral fissuresPtosisAbnormality of the pharynxAutismCompulsive behaviorsMotor stereotypyAnxietyDelayed speech and language developmentIntellectual disabilitySeizureHypotoniaGlobal developmental delayGrowth delayHypernasal speechVentricular septal defectTetralogy of FallotTransposition of the great arteriesAbnormal speech patternScoliosisHypoplastic left ventricleAttention deficit hyperactivity disorderUrethral stenosisAnterior creases of earlobeAplasia/Hypoplasia of the thymusAbnormality of immune system physiologyInterrupted aortic archMidface retrusionDisplacement of the urethral meatus

Classification & Codes

MeSH Code

C567224

Orphanet Code

ORPHA:1727
chromosome 22q11.2 microduplication syndrome
MeSHC567224
OrphanetORPHA:1727
Treatments0 drug(s)
Symptoms on record40 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO