chronic recurrent multifocal osteomyelitis

MeSH: C535456ORPHA: 324964

Overview

osteomyelitis characterized by multiple foci of painful swelling of bones, mainly in the metaphyses of the long bones, in addition to the pelvis, the shoulder girdle and the spine

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with chronic recurrent multifocal osteomyelitis, sourced from HPO and Orphanet clinical annotations.

Abnormal metaphysis morphologyEdemaSkin rashPruritusAcneArthritisWeight lossAnemiaFeverInflammation of the large intestineVasculitisScoliosisBone painOsteomyelitisOsteolysisAbnormal vertebral morphologyElevated erythrocyte sedimentation ratePsoriasiform dermatitisPoor appetiteCraniofacial osteosclerosisAbnormal epiphysis morphologyCranial nerve paralysisElevated circulating C-reactive protein concentrationFatigueHyperostosisAbnormal sacroiliac joint morphologyPalmoplantar pustulosis

Classification & Codes

MeSH Code

C535456

Orphanet Code

ORPHA:324964
chronic recurrent multifocal osteomyelitis
MeSHC535456
OrphanetORPHA:324964
Treatments0 drug(s)
Symptoms on record27 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO