Churg-Strauss syndrome
MeSH: D015267ORPHA: 183
Overview
a systemic vasculitis realized as blood vessel inflammation, with symptoms asthma along with hay fever, rash and gastrointestinal bleeding
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Churg-Strauss syndrome, sourced from HPO and Orphanet clinical annotations.
SinusitisPurpuraUrticariaWeight lossIncreased total eosinophil countAsthmaPulmonary infiltratesVasculitisAutoimmunityCentral nervous system degenerationPeripheral neuropathyIncreased inflammatory responseHematuriaHypertensionSkin rashHypopigmented skin patchesGait disturbanceHypertrophic cardiomyopathyAbnormal pericardium morphologyTubulointerstitial nephritisDysphagiaNausea and vomitingAbdominal painAbnormal pleura morphologyArthralgiaRheumatoid factor positiveIncreased circulating IgE concentrationVenous thrombosisAirway obstructionFatigueMultiple mononeuropathyEosinophilic pneumoniaCytoplasmic antineutrophil antibody positivityAnti-proteinase 3 antibody positivityAnti-myeloperoxidase antibody positivityAnti-neutrophil elastase antibody positivityRenal insufficiencyProteinuriaCutis marmorataAcrocyanosisArthritisSubcutaneous noduleCongestive heart failureMyocardial infarctionFeverGastroesophageal refluxMalabsorptionRespiratory insufficiencyHemoptysisPleural effusionTransient ischemic attackMyalgiaHemiplegia/hemiparesisIntestinal obstructionRecurrent intrapulmonary hemorrhageCranial nerve paralysisCrescentic glomerulonephritisCoughMyocarditisGastrointestinal eosinophiliaNasal polyposisEndocarditisMyositisGlomerulopathyPapuleCutaneous granuloma
Classification & Codes
MeSH Code
D015267Orphanet Code
ORPHA:183Churg-Strauss syndrome
| MeSH | D015267 |
| Orphanet | ORPHA:183 |
| Treatments | 0 drug(s) |
| Symptoms on record | 66 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO