classic progressive supranuclear palsy syndrome

ORPHA: 240071

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with classic progressive supranuclear palsy syndrome, sourced from HPO and Orphanet clinical annotations.

Postural instabilityFallsSlow saccadic eye movementsMental deteriorationConjunctival hyperemiaDecreased lacrimationBlurred visionBlepharospasmPhotophobiaSocial and occupational deteriorationImpulsivitySlowed slurred speechSupranuclear gaze palsyNeuromuscular dysphagiaParkinsonismAxial muscle stiffnessBradykinesiaGait imbalanceVertical supranuclear gaze palsyAxial dystoniaAkinesiaTremorDysarthriaProgressive extrapyramidal muscular rigidityDystoniaAbnormal saccadic eye movementsAbnormal pyramidal signParkinsonism with favorable response to dopaminergic medication

Classification & Codes

Orphanet Code

ORPHA:240071
classic progressive supranuclear palsy syndrome
OrphanetORPHA:240071
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO