cleft lip and cleft palate

ICD-10: Q35ORPHA: 199306

Overview

congenital malformations caused by the failure of embryonic structures of the lip and/or palate to fuse

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with cleft lip and cleft palate, sourced from HPO and Orphanet clinical annotations.

Abnormality of dental eruptionCleft palateOrofacial cleftVelopharyngeal insufficiencyRecurrent otitis mediaDelayed speech and language developmentPoor suckFeeding difficulties in infancySpeech articulation difficultiesUnilateral cleft palateOral-pharyngeal dysphagiaConductive hearing impairmentDental malocclusionHypernasal speechMalnutritionPeg-shaped maxillary lateral incisorsPalate fistulaAbnormal number of permanent teethBilateral cleft palateAgenesis of lateral incisorHypoplasia of the maxilla

Classification & Codes

ICD-10 Code

Q35

Orphanet Code

ORPHA:199306
cleft lip and cleft palate
ICD-10Q35
OrphanetORPHA:199306
Treatments0 drug(s)
Symptoms on record21 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO