cleft lip-palate-ectodermal dysplasia syndrome
MeSH: C536726ORPHA: 3253
Overview
Human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with cleft lip-palate-ectodermal dysplasia syndrome, sourced from HPO and Orphanet clinical annotations.
Small scrotumAbnormality of the ureterHypogonadismAbnormality of the dentitionCleft upper lipMicrognathiaMacrotiaProtruding earWide nasal bridgeDownslanted palpebral fissuresSynophrysHypodontiaCarious teethAnodontiaAbnormal dental enamel morphologyHypohidrosisEctodermal dysplasiaPalmoplantar hyperkeratosisIntellectual disabilitySeizureAlopeciaToe syndactylyDystrophic toenailAbnormal speech patternRecurrent respiratory infectionsEEG abnormalityHighly arched eyebrowHyperlordosisPili tortiSparse lateral eyebrowFinger syndactylyAbnormal dental morphologyWide intermamillary distanceAbnormal dermatoglyphicsBilateral single transverse palmar creasesSparse hairDystrophic fingernailsNail dystrophyHypoplasia of the zygomatic boneMidface retrusionAplasia/Hypoplasia of the eyebrow
Classification & Codes
MeSH Code
C536726Orphanet Code
ORPHA:3253cleft lip-palate-ectodermal dysplasia syndrome
| MeSH | C536726 |
| Orphanet | ORPHA:3253 |
| Treatments | 0 drug(s) |
| Symptoms on record | 41 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO