Clouston syndrome

ORPHA: 189

Contents

1. Overview
2. Available Treatments
3. Clinical Presentation
4. Classification & Codes

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Clouston syndrome, sourced from HPO and Orphanet clinical annotations.

Sparse eyelashesPalmoplantar hyperkeratosisPalmoplantar keratodermaAlopeciaSparse hairNail dystrophySparse eyebrowHearing impairmentHyperpigmentation of the skinThickened skinSmall nailAnonychiaSparse scalp hairFine hairSparse axillary hairAbsent axillary hairAbsent eyebrowSparse pubic hairAbsent pubic hairGeneralized hypotrichosisBrittle scalp hairHypopigmentation of hairSlow-growing nailsAbnormal metacarpophalangeal joint morphologyCobblestone-like hyperkeratosisHyperkeratotic papuleClubbing of fingers

Classification & Codes

Orphanet Code

ORPHA:189

Clouston syndrome

Orphanet	`ORPHA:189`
Treatments	0 drug(s)
Symptoms on record	27 signs
Status	published

Factual Authority

Last Updated3/20/2026

Clinical DataHPO · Orphanet

Drug DataFDA · EMA · CDSCO